In vivo Toxicologie

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Following the demands of the regulatory authorities, different toxicology studies may be conducted:
  • Acute
  • Subacute
  • Chronic
  • Reproduction
  • Carcinogenicity

 

LAUS offers its customers the complete spectrum including necessary analytical determinations. The studies are performed in cooperation with qualified GLP test facilities (CRO).

 

Guideline Description
OECD 423 Acute Oral Toxicity Rat
OECD 402 Acute Dermal Toxicity Rat
OECD 403 Acute Inhalation Toxicity Rat
OECD 404 Acute Skin Irritation, Corrosion: Rabbit
OECD 405 Acute Eye Irritation: Rabbit
OECD 406 Skin Sensitisation following:
- Magnusson-Kligman (Guinea pig)
- Bühler (Guinea pig)
OECD 407 Subacute toxicity (repeated dose): Rat (28-day study)
OECD 408 Subacute toxicity (repeated dose): Rat (90-day study)
OECD 414 Prenatal Development Toxicity
OECD 421 Screening for Reproduction Toxicity
OECD 429 Skin Sensitisation – Local Lymph Node Assay (LLNA)
OECD 474 Micronucleus Test in mammalian erythrocytes

 

The study you need is not listed? Please contact us.
We’ll prepare you an individual offer for your needs.