OECD Guidelines
Section 1: Physical Chemical Properties
- Summary of Considerations in the Report from the OECD Expert Group on Physical Chemistry
OECD Guidelines for the Testing of Chemicals - Test Nr. 101: UV-VIS Absorption Spectra
OECD Guidelines for the Testing of Chemicals - Test Nr. 102: Melting Point/ Melting Range
OECD Guidelines for the Testing of Chemicals - Test Nr. 103: Boiling Point
OECD Guidelines for the Testing of Chemicals - Test Nr. 104: Vapour Pressure
OECD Guidelines for the Testing of Chemicals - Test Nr. 105: Water Solubility
OECD Guidelines for the Testing of Chemicals - Test Nr. 106: Adsorption -- Desorption Using a Batch Equilibrium Method
OECD Guidelines for the Testing of Chemicals - Test Nr. 107: Partition Coefficient (n-octanol/water): Shake Flask Method
OECD Guidelines for the Testing of Chemicals - Test Nr. 108: Complex Formation Ability in Water
OECD Guidelines for the Testing of Chemicals - Test Nr. 109: Density of Liquids and Solids
OECD Guidelines for the Testing of Chemicals - Test Nr. 110: Particle Size Distribution/ Fibre Length and Diameter Distributions
OECD Guidelines for the Testing of Chemicals - Test Nr. 111: Hydrolysis as a Function of pH
OECD Guidelines for the Testing of Chemicals - Test Nr. 112: Dissociation Constants in Water
OECD Guidelines for the Testing of Chemicals - Test Nr. 113: Screening Test for Thermal Stability and Stability in Air
OECD Guidelines for the Testing of Chemicals - Test Nr. 114: Viscosity of Liquids
OECD Guidelines for the Testing of Chemicals - Test Nr. 115: Surface Tension of Aqueous Solutions
OECD Guidelines for the Testing of Chemicals - Test Nr. 116: Fat Solubility of Solid and Liquid Substances
OECD Guidelines for the Testing of Chemicals - Test Nr. 117: Partition Coefficient (n-octanol/water), HPLC Method
OECD Guidelines for the Testing of Chemicals - Test Nr. 118: Determination of the Number-Average Molecular Weight and the Molecular Weight Distribution of Polymers using Gel Permeation Chromatography
OECD Guidelines for the Testing of Chemicals - Test Nr. 119: Determination of the Low Molecular Weight Content of a Polymer Using Gel Permeation Chromatography
OECD Guidelines for the Testing of Chemicals - Test Nr. 120: Solution/Extraction Behaviour of Polymers in Water
OECD Guidelines for the Testing of Chemicals - Test Nr. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)
OECD Guidelines for the Testing of Chemicals - Test Nr. 123: Partition Coefficient (1-Octanol/Water): Slow-Stirring Method
OECD Guidelines for the Testing of Chemicals
Section 2: Effects on Biotic Systems
- Summary of Considerations in the Report from the OECD Expert Group on Ecotoxicology
OECD Guidelines for the Testing of Chemicals - OECD Test No. 201: Alga, Growth Inhibition Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 202: Daphnia sp. Acute Immobilisation Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 203: Fish, Acute Toxicity Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 204: Fish, Prolonged Toxicity Test: 14-Day Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 205: Avian Dietary Toxicity Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 206: Avian Reproduction Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 207: Earthworm, Acute Toxicity Tests
OECD Guidelines for the Testing of Chemicals - OECD Test No. 208: Terrestrial Plant Test: Seedling Emergence and Seedling Growth Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 209: Activated Sludge, Respiration Inhibition Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 210: Fish, Early-Life Stage Toxicity Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 211: Daphnia magna Reproduction Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 212: Fish, Short-term Toxicity Test on Embryo and Sac-Fry Stages
OECD Guidelines for the Testing of Chemicals - OECD Test No. 213: Honeybees, Acute Oral Toxicity Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 214: Honeybees, Acute Contact Toxicity Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 215: Fish, Juvenile Growth Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 216: Soil Microorganisms: Nitrogen Transformation Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 217: Soil Microorganisms: Carbon Transformation Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 218: Sediment-Water Chironomid Toxicity Using Spiked Sediment
OECD Guidelines for the Testing of Chemicals - OECD Test No. 219: Sediment-Water Chironomid Toxicity Using Spiked Water
OECD Guidelines for the Testing of Chemicals - OECD Test No. 220: Enchytraeid Reproduction Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 221: Lemna sp. Growth Inhabition Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 222: Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei)
OECD Guidelines for the Testing of Chemicals - OECD Test No. 224: Determination of the Inhibition of the Activity of Anaerobic Bacteria: Reduction of Gas Production from Anaerobically Digesting (sewage) Sludge
OECD Guidelines for the Testing of Chemicals - OECD Test No. 225: Sediment-Water Lumbriculus Toxicity Test Using Spiked Sediment
OECD Guidelines for the Testing of Chemicals - OECD Test No. 226: Predatory mite (Hypoaspis (Geolaelaps) aculeifer) reproduction test in soil
OECD Guidelines for the Testing of Chemicals - OECD Test No. 227: Terrestrial Plant Test: Vegetative Vigour Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 228: Determination of Developmental Toxicity of a Test Chemical to Dipteran Dung Flies(Scathophaga stercoraria L. (Scathophagidae), Musca autumnalis De Geer (Muscidae))
OECD Guidelines for the Testing of Chemicals - OECD Test No. 229: Fish Short Term Reproduction Assay
OECD Guidelines for the Testing of Chemicals - OECD Test No. 230: 21-day Fish Assay: A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition
OECD Guidelines for the Testing of Chemicals - Test No 231: Amphibian Metamorphosis Assay
OECD Guidelines for the Testing of Chemicals - OECD Test No. 232: Collembolan Reproduction Test in Soil
OECD Guidelines for the Testing of Chemicals
Section 3: Degradation and Accumulation
- Revised Introduction to the OECD Guidelines for Testing of Chemicals, Section 3
OECD Guidelines for the Testing of Chemicals - OECD Test No. 301: Ready Biodegradability
OECD Guidelines for the Testing of Chemicals - OECD Test No. 302A: Inherent Biodegradability: Modified SCAS Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 302B: Inherent Biodegradability: Zahn-Wellens/ EVPA Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 302C: Inherent Biodegradability: Modified MITI Test (II)
OECD Guidelines for the Testing of Chemicals - OECD Test No. 303: Simulation Test - Aerobic Sewage Treatment -- A: Activated Sludge Units; B: Biofilms
OECD Guidelines for the Testing of Chemicals - OECD Test No. 304A: Inherent Biodegradability in Soil
OECD Guidelines for the Testing of Chemicals - OECD Test No. 305: Bioconcentration: Flow-through Fish Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 306: Biodegradability in Seawater
OECD Guidelines for the Testing of Chemicals - OECD Test No. 307: Aerobic and Anaerobic Transformation in Soil
OECD Guidelines for the Testing of Chemicals - OECD Test No. 308: Aerobic and Anaerobic Transformation in Aquatic Sediment Systems
OECD Guidelines for the Testing of Chemicals - OECD Test No. 309: Aerobic Mineralisation in Surface Water - Simulation Biodegradation Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 310: Ready Biodegradability - CO2 in sealed vessels (Headspace Test)
OECD Guidelines for the Testing of Chemicals - OECD Test No. 311: Anaerobic Biodegradability of Organic Compounds in Digested Sludge: by Measurement of Gas Production
OECD Guidelines for the Testing of Chemicals - OECD Test No. 312: Leaching in Soil Columns
OECD Guidelines for the Testing of Chemicals - OECD Test No. 313: Estimation of Emissions from Preservative - Treated Wood to the Environment: Laboratory Method for Wooden Commodities that are not Covered and are in Contact with Fresh Water or Seawater
OECD Guidelines for the Testing of Chemicals - OECD Test No. 314: Simulation Tests to Assess the Biodegradability of Chemicals Discharged in Wastewater
OECD Guidelines for the Testing of Chemicals - OECD Test No. 315: Bioaccumulation in Sediment-dwelling Benthic Oligochaetes
OECD Guidelines for the Testing of Chemicals - OECD Test No. 316: Phototransformation of Chemicals in Water - Direct Photolysis
OECD Guidelines for the Testing of Chemicals
Section 4: Health Effects
- OECD Test No. 401: Acute Oral Toxicity
OECD Guidelines for the Testing of Chemicals - OECD Test No. 402: Acute Dermal Toxicity
OECD Guidelines for the Testing of Chemicals - OECD Test No. 404: Acute Dermal Irritation/Corrosion
OECD Guidelines for the Testing of Chemicals - OECD Test No. 405: Acute Eye Irritation/Corrosion
OECD Guidelines for the Testing of Chemicals - OECD Test No. 406: Skin Sensitisation
OECD Guidelines for the Testing of Chemicals - OECD Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents
OECD Guidelines for the Testing of Chemicals - OECD Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents
OECD Guidelines for the Testing of Chemicals - OECD Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents
OECD Guidelines for the Testing of Chemicals - OECD Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 411: Subchronic Dermal Toxicity: 90-day Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 412: Subacute Inhalation Toxicity: 28-Day Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 413: Subchronic Inhalation Toxicity: 90-day Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 414: Prenatal Development Toxicity Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 415: One-Generation Reproduction Toxicity Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 416: Two-Generation Reproduction Toxicity
OECD Guidelines for the Testing of Chemicals - OECD Test No. 417: Toxicokinetics
OECD Guidelines for the Testing of Chemicals - OECD Test No. 418: Delayed Neurotoxicity of Organophosphorus Substances Following Acute Exposure
OECD Guidelines for the Testing of Chemicals - OECD Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study
- OECD Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure
OECD Guidelines for the Testing of Chemicals - OECD Test No. 421: Reproduction/Developmental Toxicity Screening Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 423: Acute Oral toxicity - Acute Toxic Class Method
OECD Guidelines for the Testing of Chemicals - OECD Test No. 424: Neurotoxicity Study in Rodents
OECD Guidelines for the Testing of Chemicals - OECD Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure
OECD Guidelines for the Testing of Chemicals - OECD Test No. 426: Developmental Neurotoxicity Study
OECD Guidelines for the Testing of Chemicals - OECD Test No. 427: Skin Absorption: In Vivo Method
OECD Guidelines for the Testing of Chemicals - OECD Test No. 428: Skin Absorption: In Vitro Method
OECD Guidelines for the Testing of Chemicals - OECD Test No. 429: Skin Sensitisation: Local Lymph Node Assay
OECD Guidelines for the Testing of Chemicals - OECD Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER)
OECD Guidelines for the Testing of Chemicals - OECD Test No. 431: In Vitro Skin Corrosion: Human Skin Model Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 432: In Vitro 3T3 NRU Phototoxicity Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion
OECD Guidelines for the Testing of Chemicals - OECD Test No. 440: Uterotrophic Bioassay in Rodents: A short-term screening test for oestrogenic properties
OECD Guidelines for the Testing of Chemicals - OECD Test No. 452: Chronic Toxicity Studies
OECD Guidelines for the Testing of Chemicals - OECD Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies
OECD Guidelines for the Testing of Chemicals - OECD Test No. 471: Bacterial Reverse Mutation Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 473: In vitro Mammalian Chromosome Aberration Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 474: Mammalian Erythrocyte Micronucleus Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 475: Mammalian Bone Marrow Chromosome Aberration Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 476: In vitro Mammalian Cell Gene Mutation Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 477: Genetic Toxicology: Sex-Linked Recessive Lethal Test in Drosophila melanogaster
OECD Guidelines for the Testing of Chemicals - OECD Test No. 478: Genetic Toxicology: Rodent Dominant Lethal Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells
OECD Guidelines for the Testing of Chemicals - OECD Test No. 480: Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay
OECD Guidelines for the Testing of Chemicals - OECD Test No. 481: Genetic Toxicology: Saacharomyces cerevisiae, Miotic Recombination Assay
OECD Guidelines for the Testing of Chemicals - OECD Test No. 482: Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro
OECD Guidelines for the Testing of Chemicals - OECD Test No. 483: Mammalian Spermatogonial Chromosome Aberration Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 484: Genetic Toxicology: Mouse Spot Test
OECD Guidelines for the Testing of Chemicals - OECD Test No. 485: Genetic toxicology, Mouse Heritable Translocation Assay
OECD Guidelines for the Testing of Chemicals - OECD Test No. 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo
OECD Guidelines for the Testing of Chemicals - OECD Test No. 403: Acute Inhalation Toxicity
OECD Guidelines for the Testing of Chemicals - OECD Test No. 436: Acute Inhalation Toxicity - Acute Toxic Class Method
OECD Guidelines for the Testing of Chemicals - OECD Test No. 437: Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants
OECD Guidelines for the Testing of Chemicals - OECD Test No. 438: Isolated Chicken Eye Test Method for Identifying Ocular Corrosives and Severe Irritants
OECD Guidelines for the Testing of Chemicals - OECD Test No. 441: Hershberger Bioassay in Rats: A Short-term Screening Assay for (Anti)Androgenic Properties
OECD Guidelines for the Testing of Chemicals - OECD Test No. 451: Carcinogenicity Studies
OECD Guidelines for the Testing of Chemicals - OECD Test No. 455: The Stably Transfected Human Estrogen Receptor-á Transcriptional Activation Assay for Detection of Estrogenic Agonist-Activity of Chemicals
OECD Guidelines for the Testing of Chemicals